Pharmacology: Antihypertensive Medication – PO (Oral)

Hypertension (HTN)

PO (Oral) Antihypertensive Medication

Beta Blockers

  • Beta Blockade:
    • Beta-1: Decrease Heart Rate & Contractility
    • Beta-2: Decrease Blood Pressure & Bronchodilation
  • Nonselective Agents – Both Beta-1 & Beta-2 Activity
    • Propranolol (Inderal)
    • Carvedilol (Coreg)
    • Labetalol (Trandate)
    • Nadolol (Corgard)
    • Nebivolol (Bystolic)
    • Pindolol (Visken)
    • Sotalol (Betapace)
    • Timolol (Blocadren)
  • Cardio-Selective Agents – Only Beta-1 Activity
    • Metoprolol (Lopressor, Toprol-XL)
    • Esmolol (Brevibloc)
    • Acebutolol (Sectral)
    • Atenolol (Tenormin)

Calcium Channel Blocker (CCB)

  • Dihydropyridine Agents – Decrease Systemic Vascular Resistance
    • Amlodipine (Norvasc)
    • Nicardipine (Cardene)
    • Nifedipine
  • Phenylalkylamine Agents – Cardio-Selective & Decrease Myocardial Oxygen Demand
    • Verapamil
    • Gallopamil
    • Fendiline
  • Benzothiazepine – Both Cardiac & Systemic Vascular Activity
    • Diltiazem (Cardizem)

Angiotensin Converting Enzyme (ACE) Inhibitor

  • Lisinopril
  • Enalapril
  • Captopril
  • Benazepril
  • Imidapril
  • Alacepril
  • Zofenopril

Angiotensin II Receptor Blocker (ARB)

  • Losartan
  • Valsartan
  • Irbesartan
  • Candesartan

Thiazide Diuretic

  • Hydrochlorothiazide (HCTZ)
  • Chlorthalidone

Alpha Blockers

  • Prazosin
  • Doxazosin
  • Terazosin