Skin & Soft Tissue: Dermatofibroma (Benign Fibrous Histiocytoma) Dermatofibroma (Benign Fibrous Histiocytoma) BasicsBenign Proliferation of Dermal FibroblastsMost Common in AdultsPresentationSolitary Firm NoduleOften HyperpigmentedDiameter 3-10 mm, Can Be LargerFixed to Subcutaneous TissueDimple When PinchedMost Common on Lower ExtremitiesDiagnosisClinical (Based on History and Physical Exam)May Require Biopsy if UncertainTreatmentGenerally Require No TreatmentIndications for Excision:SymptomaticConcern for MalignancyPatient Preference (Cosmesis) Dermatofibroma 1 References Mohammad 2018. Wikimedia Commons. (License: CC BY-SA-4.0)