Breast: Intraductal Papilloma
Intraductal Papilloma
Basics
- Definition: Benign Tumor of Ductal Epithelial Cells Within Mammary Ducts
- Solitary Intraductal Papilloma: Single Papilloma
- Usually Found Centrally
- Diffuse Papillomatosis: ≥ 5 Papillomas Within a Localized Breast Segment
- Solitary Intraductal Papilloma: Single Papilloma
- 5-15% Risk of Harboring Atypia, DCIS or Malignancy
Presentation
- Mostly Asymptomatic & Found Incidentally
- May Be Palpable
- Most Common Cause of Bloody/Pathologic Nipple Discharge
Intraductal Papilloma on Ductoscopy 1
Diagnosis
- Initial Evaluation: Imaging (Mammogram, US, MRI or Ductogram/Galactography)
- Diagnosis: Core Needle Biopsy (CNB)
- *See Breast: Breast Mass Evaluation
Treatment
- Treatment: Surgical Excision
- *Consider Terminal Duct Excision if No Lesion is Identified on Imaging
Intraductal Papilloma on US 2
Intraductal Papilloma on Histology 3
References
- Al Sarakbi W, Worku D, Escobar PF, Mokbel K. Breast papillomas: current management with a focus on a new diagnostic and therapeutic modality. Int Semin Surg Oncol. 2006 Jan 17;3:1. (License: CC BY-2.0)
- Dilmen N. Wikimedia Commons. (License: CC BY-SA-3.0)
- Kayb S. Wikimedia Commons. (License: CC BY-SA-4.0)