Inflammation with Associated Thrombus of Superficial Veins
Most Common in the Lower Extremities
Generally Benign & Self-Limited but Can Extend into Deep Veins
High-Risk of Concomitant VTE:
DVT (6-44%)
Asymptomatic PE (20-33%)
Symptomatic PE (2-13%)
Presentation
Palpable Cord-Like Mass
Erythema
Pain
Swelling
Superficial Venous Thrombophlebitis 1
Superficial Venous Thrombophlebitis on US 2
Variations
Suppurative Thrombophlebitis
Infected (Fever & Purulence)
Risk for Septicemia
Most Common Cause: Peripheral IV
Drug Abuse Also Common
Most Common Organism: S aureus
Superficial Migratory Thrombophlebitis
Recurrent Migratory & Unprovoked
Associated with Hypercoagulability from Carcinoma (Trousseau’s Sign)
Should Prompt Search for Occult Malignancy (CT Abdomen, etc.)
Mondor Disease
Definition: Acute SVT of the Chest Wall
Most Common Cause: Idiopathic
Other Causes: Trauma, Surgery or Malignancy
Most Common Site: Lateral Thoracic Vein in Lower Outer Quadrant
Need Imaging to Rule Out Malignant Cause
*Mondor Disease of the Penis – Thrombophlebitis of the Superficial Dorsal Vein of the Penis
Superficial Migratory Thrombophlebitis Associated with Pancreatic Cancer 3
Mondor Disease 4
Treatment
Low-Risk of DVT: NSAIDs, Warm Compress & Elevation
Increased-Risk of DVT: Anticoagulation for 45 Days
SVT < 3 cm of Saphenofemoral Junction Should Receive Anticoagulation
Suppurative: Antibiotics & Remove Foreign Body/Catheter if Able
Vein Excision Indications:
Within 1 cm of Deep Vein Junction
Suppurative with Sepsis (Historically Was Excised More Frequently)
References
Owlia MB, Salimzadeh A, Alishiri G, Kargar S. Ischemic toes after venous thromboembolism: a difficult differential diagnosis with good response to combination therapy-a case report. Case Rep Med. 2012;2012:403685.(License: CC BY-3.0)
Kim SY, Park JS, Ryu KN, Jin W, Park SY. Various tumor-mimicking lesions in the musculoskeletal system: causes and diagnostic approach. Korean J Radiol. 2011 Mar-Apr;12(2):220-31. (License: CC BY-NC-3.0)
Thayalasekaran S, Liddicoat H, Wood E. Thrombophlebitis migrans in a man with pancreatic adenocarcinoma: a case report. Cases J. 2009 Apr 29;2:6610. (License: CC BY-3.0)
Viana GA, Okano FM. Superficial thrombophlebitis (Mondor’s Disease) after breast augmentation surgery. Indian J Plast Surg. 2008 Jul;41(2):219-21. (License: CC BY-2.0)