Urology: Vesicoureteral Reflux (VUR)

Vesicoureteral Reflux (VUR)

Definition

  • Retrograde Urine Reflux from Bladder into the Ureters

Presentation

  • Hydronephrosis
  • Recurrent UTI & Pyelonephritis
  • Renal Injury/Failure

Diagnosis

  • Diagnosis: Voiding Cystourethrogram (Gold Standard)
  • Alternative Imaging: Radionuclide Cystogram or US
  • Also Screen for Bladder & Bowel Dysfunction

International Study Classification

  • Grade I: Urine Reflux into the Ureter Only
  • Grade II: Urine Reflux into the Ureter, Renal Pelvis & Calyces, Without Dilation
  • Grade III: Mild-Moderate Dilation/Tortuosity of the Ureter & Renal Pelvis with Minimal Blunting of the Fornices
  • Reflux with Mild Dilation of the Ureter & Pyelocalyceal System
  • Grade IV: Moderate Dilation/Tortuosity of the Ureter & Renal Pelvis/Calyces with Complete Obliteration of the Sharp Angles of the Fornices but Maintenance of the Papillary Impressions in the Majority of the Calyces
  • Grade V: Gross Dilation/Tortuosity of the Ureter & Renal Pelvis/Calyces with No Visible Papillary Impressions in the Majority of the Calyces

Treatment

  • No Ureter Dilation (Grade I-II): Conservative Management
  • Ureter Dilation (Grade III-V): Surgical Reimplantation (Long Bladder Segment) or Endoscopic Correction

Vesicoureteral Reflux on Voiding Cystourethrogram, Grade 4 with Intrarenal Reflux on Left, Grade 3 on Right 1

References

  1. Yüksel S. Intrarenal reflux. NDT Plus. 2008 Jun;1(3):188-9. (License: CC BY-NC-4.0)